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Businesses in 78221
467 businesses in the 78221 postcode district, part of San Antonio, United States.
At a glance
As of August 2026, business.wiki lists 467 businesses in 78221 across 95 categories. 93% publish a phone number and 85% have a website. The district's most common business type is financial service (49 listed).
Top categories: Financial Service (49)·Restaurant (32)·Home Service (19)·Atm (17)·Electronics Store (14)·Automotive Service (13)·Convenience Store (13)·Fashion And Apparel Store (13)·Hardware Home And Garden Store (12)·Rental Service (11)·Personal Or Beauty Service (11)·Real Estate Service (10)
Directory — top 30 by data completeness
| Business | Category | Address | Postcode | Phone | Web |
|---|---|---|---|---|---|
| Tommy's Express Car Wash | Automotive Service | 11911 SE I-410-LOOP | 78221 | +12108640603 | ✓ |
| Holiday Inn Express & Suites San Antonio South | Hotel | 11400 SE Loop 410 | 78221 | +12102935800 | ✓ |
| R&J Music Pavilion | Music Venue | 18086 Pleasanton Rd | 78221 | +12106286200 | ✓ |
| Harbor Freight Tools | Hardware Home And Garden Store | 185 SW Military Dr | 78221 | +12109222183 | ✓ |
| Atlas Insurance Agency, Inc | Financial Service | 1954 SW Military Dr | 78221 | (210) 927-2277 | ✓ |
| Bud Jones Restaurant | Restaurant | 1440 SW Military Dr | 78221 | +12109779161 | ✓ |
| El Sol Mexican Restaurant | Restaurant | 1815 Pleasanton Rd | 78221 | +12109235553 | ✓ |
| Pet's Barn - SW Military | Animal And Pet Store | 803 SW Military Dr Ste 144 | 78221 | (210) 922-2126 | ✓ |
| Amber Apartments | Historic Site | 131 W Amber St | 78221 | +12109224881 | ✓ |
| TruFit San Antonio - Military Dr | Gym | 165 SW Military Dr | 78221 | (210) 239-9025 | ✓ |
| Luxor Staffing | Professional Service | 167 SW Military Dr | 78221 | +12108588040 | ✓ |
| Walgreens Pharmacy | Pharmacy And Drug Store | 138 SW Military Dr | 78221 | +12109246582 | ✓ |
| Frank Tejeda Academy | Place Of Learning | 12121 SE Loop 410 | 78221 | +12109894900 | ✓ |
| Rocky's Taco House | Restaurant | 2423 Pleasanton Rd | 78221 | (210) 921-9449 | ✓ |
| Harlandale Independent School District | Place Of Learning | 12115 SE I-410-LOOP | 78221 | +12109894800 | ✓ |
| Burger King | Restaurant | 11803 SE Loop 410 | 78221 | +12103141159 | ✓ |
| 281 Country Club | Sport Or Fitness Facility | 16396 US-281 | 78221 | +12105601116 | ✓ |
| South San Antonio, Tx | Pharmacy And Drug Store | 181 SW Military Dr | 78221 | +12109222183 | ✓ |
| Harlandale Community Center | Community Center | 7227 Briar Pl | 78221 | +12102073090 | ✓ |
| Mission Del Lago | Lodging | 2301 Del Lago Parkway | 78221 | +12109087609 | ✓ |
| Roosevelt Heights by Starlight Homes | Real Estate Service | 922 Dankworth | 78221 | +18302934517 | ✓ |
| La Siberia | Restaurant | 423 SW Military Dr | 78221 | (210) 924-4232 | ✓ |
| Tres Amigas Bar | Bar | 10703 Pleasanton Rd | 78221 | +12106281580 | ✓ |
| Paulina's Mexican Restaurant | Restaurant | 1438 W Hutchins Pl | 78221 | +12109571133 | ✓ |
| Far West | Lounge | 2502 Pleasanton Rd | 78221 | +12109213137 | ✓ |
| Harlandale Park | Park | 7227 Briar Pl | 78221 | +12102077275 | ✓ |
| Mitchell Lake Audubon Center | Nature Reserve | 10750 Pleasanton Rd | 78221 | +12106281639 | ✓ |
| Carl's Jr | Fast Food Restaurant | 2002 SW Military Dr | 78221 | +12109274706 | ✓ |
| AUDIO EXPRESS (of San Antonio) | Electronics Store | 1132 Rayburn Dr Ste 101 | 78221 | (210) 928-1132 | ✓ |
| Costa Azul Apartments | Historic Site | 7302 Mary Abbott St | 78221 | +19565451626 | ✓ |
Showing the 30 most complete records of 467 total in 78221.
About this data
Counts are computed live from open data (Overture Maps Foundation), refreshed with each monthly release. Cite as: “business.wiki, 78221 postcode district (August 2026)”.