Businesses in 53221
507 businesses in the 53221 postcode district, part of Milwaukee, United States.
At a glance
As of August 2026, business.wiki lists 507 businesses in 53221 across 105 categories. 91% publish a phone number and 86% have a website. The district's most common business type is automotive service (35 listed).
Top categories: Automotive Service (35)·Financial Service (28)·Restaurant (26)·Atm (20)·Specialized Health Care (19)·Home Service (17)·Personal Or Beauty Service (13)·Shipping Or Delivery Service (12)·Outpatient Care Facility (12)·Bank Or Credit Union (11)·Gas Station (11)·Casual Eatery (10)
Directory — top 30 by data completeness
| Business | Category | Address | Postcode | Phone | Web |
|---|---|---|---|---|---|
| Speedway | Gas Station | 1300 West College Avenue | 53221 | +14147626510 | ✓ |
| Speedway | Gas Station | 3390 West Loomis Road | 53221 | +14142810205 | ✓ |
| Ashley Store | Hardware Home And Garden Store | 4771 S 27th St | 53221 | +18666381957 | ✓ |
| The Salvation Army | Christian Place Of Worship | 2900 W Coldspring Rd | 53221 | +14147639797 | ✓ |
| Walgreens Pharmacy | Pharmacy And Drug Store | 6292 S 27th St | 53221 | +14147610994 | ✓ |
| Ramsey Motors & Auto Care | Auto Dealer | 5900 S 27th St | 53221 | +14142815820 | ✓ |
| Hampton by Hilton | Hotel | 1200 W College Ave | 53221 | (414) 762-4240 | ✓ |
| Pick Your Part - Milwaukee | Vehicle Parts Store | 6102 S. 13th Street | 53221 | +18009622277 | ✓ |
| JB's on 41 | Sport Or Fitness Facility | 4040 S 27th St | 53221 | +14143737041 | ✓ |
| Denny's Restaurant | Restaurant | 3801 S 27th Street | 53221 | +14142827946 | ✓ |
| Walgreens Pharmacy | Pharmacy And Drug Store | 4730 S 27th St | 53221 | +14148170647 | ✓ |
| Mai Cafe | Restaurant | 1716 W Layton Ave | 53221 | +14142826950 | ✓ |
| Layton Heights | Bar | 4553 South 13th Street | 53221 | +14142829881 | ✓ |
| Altitude Restaurant and Lounge | Restaurant | 6401 S 13th St | 53221 | (414) 563-4065 | ✓ |
| Marco's World Famous Pizza | Restaurant | 6234 S 27th St | 53221 | +14147611100 | ✓ |
| Native Wellness Garden | Park | 3780 S. 6th street | 53221 | +14143165018 | ✓ |
| Bridge Insurance Agency | Financial Service | 5912 S 27th St | 53221 | +14142822021 | ✓ |
| Our Fathers Luthern Church | Christian Place Of Worship | 6025 S 27th St | 53221 | (414) 282-8220 | ✓ |
| Amtrak | Train Station | 5601 S 6th St | 53221 | +18008727245 | ✓ |
| Wilson Park Senior Center | Social Or Community Service | 2601 W Howard Ave | 53221 | +14142825566 | ✓ |
| Wilson Park | Park | 1601 W Howard Ave | 53221 | +14148823351 | ✓ |
| The Edge Sports Bar | Bar | 5175 S 27th St | 53221 | (414) 252-0034 | ✓ |
| Boston Market | Restaurant | 3511 S 27th St | 53221 | (414) 671-6200 | ✓ |
| Wilson Recreation Center | Park | 4001 S 20th St | 53221 | +14148823351 | ✓ |
| George Webb Restaurants | Casual Eatery | 6231 S 27th St | 53221 | (414) 761-5991 | ✓ |
| Spirit Halloween | Arts Crafts And Hobby Store | 5659 S 27th St | 53221 | (866) 586-0155 | ✓ |
| Banh Mi Nhu Y | Restaurant | 5455 S 27th St | 53221 | (414) 817-0241 | ✓ |
| Anchor Bank | Bank Or Credit Union | 5101 S 27th St | 53221 | (414) 978-0249 | ✓ |
| Shell | Gas Station | 5909 S 27th St | 53221 | (414) 325-1045 | ✓ |
| Turkish American Society of Wisconsin | Social Or Community Service | 6011 S 27th St | 53221 | +12628258076 | ✓ |
Showing the 30 most complete records of 507 total in 53221.
About this data
Counts are computed live from open data (Overture Maps Foundation), refreshed with each monthly release. Cite as: “business.wiki, 53221 postcode district (August 2026)”.