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Pharmacy And Drug Store in Sioux Falls
55 pharmacy and drug store businesses in Sioux Falls, United States. All Sioux Falls businesses →
At a glance
As of August 2026, business.wiki lists 55 pharmacy and drug store businesses in Sioux Falls— 0.6% of the city's 9,957 listed businesses. 96% publish a phone number and 95% have a website, spread across 28 postcode districts. The largest local presence is Lewis Drug with 7 locations in the city.
Where in Sioux Falls: 57105 (8)·57106 (7)·57108 (6)·57104 (5)·57103 (4)·57110 (3)·57103-1780 (1)·57103-4115 (1)
Chains here: Lewis Drug ×7·Walmart Pharmacy ×4·Walgreens ×3·Walgreens Pharmacy ×3
Directory — top 30 by data completeness
| Business | Address | Postcode | Phone | Web |
|---|---|---|---|---|
| Walgreens | 4900 S Cliff Ave | 57108 | +16053579233 | ✓ |
| Lewis Drug | 2700 W 12th St | 57104-3701 | +16053672210 | ✓ |
| Lewis Drug | 1301 E 10th St | 57103-1780 | +16053672310 | ✓ |
| Lewis Drug | 6109 S Louise Ave | 57108-5981 | +16053672510 | ✓ |
| Lewis Stores - 26th & Sycamore, Sioux Falls | 4409 E 26th St | 57103-4115 | +16053672730 | ✓ |
| Lewis Stores - 10th & Phillips Avenue | 136 S Phillips Ave | 57104-6706 | +16053672398 | ✓ |
| Lewis Drug | 2525 S Ellis Rd | 57106-7066 | +16053672430 | ✓ |
| Walgreens Pharmacy | 2605 W 12th St | 57104 | +16053579359 | ✓ |
| Walgreens Pharmacy | 1806 S Minnesota Ave | 57105 | +16052210578 | ✓ |
| Walgreens | 1720 S Sycamore Ave | 57110 | +16052210782 | ✓ |
| Medvantx | 2503 E 54th St N | 57104-5500 | +16059783900 | ✓ |
| Sioux Falls Surgical Center Pharmacy | 910 E 20th St | 57105-1012 | +16053354202 | ✓ |
| Lewis Drug | 5500 W 41st St | 57106-1009 | +16053672610 | ✓ |
| Walgreens Pharmacy | 7120 W 41st St | 57106 | +16052210989 | ✓ |
| Walgreens | 3620 W 41st St | 57106 | +16053615600 | ✓ |
| Pharmacy Specialties and Clinic Inc. | 2333 W 57th St | 57108-5053 | +16053341672 | ✓ |
| Lewis Stores - 37th & Minnesota, Sioux Falls | 2901 S Minnesota Ave | 57105-5600 | +16053672130 | ✓ |
| Caretrends Pharmacy | 6709 S Minnesota Ave | 57108-2592 | +16053389383 | ✓ |
| Walmart Pharmacy | 5521 E Arrowhead Pkwy | 57110 | (605) 367-3206 | ✓ |
| CVS Pharmacy | 1021 S Highline Pl | 57110-1000 | +16053335601 | ✓ |
| Lewis Drug 11 Participating m | 700 E 54th St N | 57104-0682 | +16053672890 | ✓ |
| Lewis Drug | 1205 S Grange Ave | 57105-0405 | +16053282620 | ✓ |
| Walmart Pharmacy | 3209 S Louise Ave | 57106 | (605) 362-1602 | ✓ |
| Avera Pharmacy - Sioux Falls - Louise Avenue | 6100 S Louise Ave Ste 1100 | 57108 | (605) 504-1351 | ✓ |
| Lewis Drug | E. 26th St. | 57103 | (605) 367-2710 | ✓ |
| Avera Home Medical Equipment - 41st Street | 2812 W 41st St | 57105-4202 | +16053221800 | ✓ |
| Cvs Pharmacy | 3600 S Louise Ave | 57106-6326 | 16052541100 | ✓ |
| Walmart | 3209 S Louise Ave | 57106 | 6053621602 | ✓ |
| Avera Pharmacy - 69th & Louise | 6100 S Louise Ave, Suite 1100 | 57108 | 6055041351 | ✓ |
| Avera Pharmacy - McKennan Campus | 1325 S Cliff Ave Ste C | 57105 | 6053228326 | ✓ |
Showing the 30 most complete records of 55 total. Every listed business has its own page with map, nearby competitors and city context.
About this data
Counts are computed live from our database of 9,957 Sioux Falls businesses, built on open data from the Overture Maps Foundation and refreshed with each monthly release. Cite as: “business.wiki, Pharmacy And Drug Store in Sioux Falls (August 2026)”.